11th International Weber Symposium

The 11th International Weber Symposium on Innovative Fluorescence Methodologies in Biochemistry and Medicine, "Weber Symposium", was held in Punta del Este, Uruguay, on January 8-13, 2023.

SPEAKER

ORGANIZERS

PRESENTATIONS

PRESENTATIONS FREE

GALLERY

Oradores

Speakers

Leonel Malacrida

Organizing Committee

Institut Pasteur de Montevideo, and Hospital de Clínicas, Universidad de la República, Uruguay.

David M Jameson

Organizing Committee

Professor of Cell and Molecular Biology, John A Burns School of Medicine, University of Hawaii at Manoa.

Enrico Gratton

Organizing Committee

Principal Investigator of the LFD. Professor of Biomedical Engineering, Physics, and College of Medicine, University of California, Irvine.

SEE FULL LIST

Schedule

DAY 2 Monday, Jan 9, 2023

07:30

Breakfast at dining room, followed by posters and exhibits.
Chair: Gregory Reinhart

09:30

Lecture 2. Diego Presman: Insights on transcription factors and chromatin dynamics through single-molecule tracking in live cells.

10:30

Break, posters and exhibits.

11:45

Lecture 5. Luca Lanzanò: Lifetime-based super-resolution and its application to a model of oncogenesis.

12:30

Lunch

14:45

Lecture 8. Francisco Barrantes: The individual molecule and its tribe, the nanocluster: the case of the nicotinic acetylcholine receptor.

15:45

Break with posters and exhibits.

17:00

Lecture 11. Hernán Grecco: From experiments to model and back: activity flow in the apoptotic network

09:00

Lecture 1. Enrico Gratton: Multiplexing spectra and lifetime in 32 channels simultaneously.

10:00

Lecture 3. Francesco Cardarelli: Once in a (fluorescence) lifetime: from synthetic identity to biological function of nanoencapsulated drugs in biomedical applications

11:15

Chair: Leonel Malacrida

Lecture 4. Jay Knutson: Fluorescence Lifetime Microscopy : Metabolic Signaling and Analysis.

12:15

Lecture 6. Jörg Enderlein: Metal- and Graphene-Induced Energy Transfer Imaging.

14:15

Chair: David Jameson

Lecture 7. Thorsten Wohland: Computational Advances and Applications in Imaging Fluorescence Correlation Spectroscopy.

15:15

Lecture 9 Gokul Upadhyayula: Making the invisible visible: imaging subcellular dynamics in multicellular systems.

16:30

Chair: Francesco Cardarelli

Lecture 10. Amitabha Chattopadhyay: Cholesterol-dependent Endocytosis and Trafficking of GPCRs: Implications in Pathophysiology and Therapeutics.

DAY 1 Sunday, Jan 8, 2023

15:00

Registration, poster and exhibit setup

19:45

Opening lecture. David M Jameson: The seminal contributions of Gregorio Weber to modern fluorescence spectroscopy and to protein chemistry.

19:30

Welcome: Leonel Malacrida, David M Jameson, and Enrico Gratton.

20:45

Cocktail reception

DAY 3 Tuesday, Jan 10, 2023

07:30

Breakfast at dining room, followed by posters and exhibits.

09:30

Lecture 13. Ilaria Testa: From STARSS: measuring rotational diffusivity with reversible photo-switching.

10:30

Break, posters and exhibits

11:45

Lecture 16. Don Lamb: Measuring protein dynamics using smFRET

12:45

Lunch

14:30

Lecture 19. Myong: G-quadruplex as a genetic switch in transcription and translation.

15:30

Break, posters and exhibits

16:30

Lecture 22. Markita Landry: Imaging Neuromodulation in the Brain with Near-Infrared Fluorescent Nanosensors.

17:30

Lecture 24. Weber Lecturer: Alberto Diaspro: The multimodal microscope and the Plato’s allegory of the cave. Increasing knowledge by coupling fluorescence and label-free mechanisms of contrast.

09:00

Chair: Alberto Diaspro

Lecture 12. Fernando Stefani: RASTMIN: an alternative to MINFLUX that enables nanometer resolution in a laser-scanning (confocal) microscope.

10:00

Lecture 14. Adán Guerrero: Extending resolution within a single imaging frame.

11:15

Chair: Jay Knutson

Lecture 15. Rafael Piestun: Optimizing Super-resolution Localization Microscopy: Three Dimensions, Dense Scenes, Fast drift-less acquisition, and Multicolor/Multispectral Imaging.

12:15

Lecture 17. Martin Hof: Protein hydration and dynamics seen by fluorescence: TDFS and PET-FCS.

14:00

Chair: Francesco Cardarelli

Lecture 18. Valeria Levi: An unexpected partnership between SOX2 and the Glucocorticoid receptor: nothing to do together but something (unknown) in common.

15:00

Lecture 20. Luke Lavis: Designing brighter dyes for advanced fluorescence microscopy and beyond.

16:00

Chair: David Jameson

Lecture 21. Elizabeth Hinde: Fluorescence fluctuation spectroscopy of protein transport as a function of oligomeric state.

17:00

Lecture 23. Weber Thesis Award Winner: Lorenzo Scipioni: High-content determination of the cell state by Phasor S-FLIM.

DAY 4 Wednesday, Jan 11, 2023

07:30

Breakfast at dining room followed by posters and exhibit.

Confirmed short talks:

09:15

Florencia Irigoín: Study of biophysical properties of the cilium that regulate protein transport to the organelle.

09:45

Irene Carlon-Andres: Quantitative characterization of HIV-1 viruses using fluorescence lifetime correlation spectroscopy: Lifetime-based Virometry.

10:15

Natalia Philipp: Measuring protein interaction from images.

09:00

Christian Combs: Convolutional Neural Network Transformer (CNNT) for Fluorescence Microscopy Denoising with Improved Generalization and Fast Adaption.

09:30

Rajesh Ramachandran: The predicted coiled-coil motif of intrinsically disordered mitochondrial Fission Factor (Mff) functions as a lipid-sensing amphipathic helix.

10:00

Camila Oses: The dynamical organization of pluripotency transcription factors respond to differentiation cues in early S-phase.

10:30

Elaine Petroniho: Can Heparin Modulate Prion Protein Liquid-Liquid Phase Separation?

Rest of day free

DAY 5 Thursday, Jan 12, 2023

07:30

Breakfast at dining room, followed by posters and exhibits.

09:30

Lecture 26. Jerson Silva: The chameleonic behavior of p53 in health and disease: Phase separation and aggregation of mutant p53 as an emerging target in cancer.

10:30

Break, posters and exhibits

11:45

Lecture 29. Melike Lakadamyali: Super-resolution imaging of chromatin structure and dynamics in health and disease.

12:45

Lunch
Luis Bagatolli Memorial Session

14:45

Lecture 32. Susana Sanchez: Cell Membrane heterogeneity and media stiffness

15:45

Lecture 34. Soledad Celej: Exploring the phase behavior of the amyloidogenic proteins alpha-synuclein and Tau.

19:00

Symposium Banquet.

09:00

Chair: Francisco Barrantes

Lecture 25. Francesco Palomba: Advanced fluorescence microscopy techniques for the biophysical understanding of protein condensates.

10:00

Lecture 27. Melissa Birol: Imaging disordered protein systems through different scales.

11:15

Chair: Debora Foguel

Lecture 28. Joachim Mueller: Partitioning of ribonucleoprotein complexes from the cellular actin cortex.

12:15

Lecture 30. Luciano Masullo: Single-molecule localization with molecular-scale precision by raster scanning a minimum of light.

14:15

Chair: Enrico Gratton
Lecture 31. Leonel Malacrida: Accessing to cellular innards water dipolar relaxation by dimethylamino-naphthalene probes and phasor analysis of multiplexing fluorescence microscopy.

15:15

Lecture 33. David Jameson: Nanoimaging Studies on Cytoplasmic and Nuclear Arc/Arg3.1.

16:15

Break, posters and exhibits.

DAY 6 Friday, Jan 13, 2023

07:30

Breakfast at dining room, followed by posters and exhibits.

09:30

Lecture 36. Debora Foguel: The role of neutrophils and neutrophil extracellular traps (NETs) in amyloid diseases.

10:30

Break, posters and exhibits.

12:00

Lecture 39. Elliot Elson: Lipid Domain Growth Studied by iFCS

12:45

Lunch

09:00

Chair: Thorsten Wohland

Lecture 35. Michelle Digman: The phasor approach to FLIM for Metabolic profiling and Mitometer for tracking phenotypic changes in mitochondria in cancer cells.